Biological and Active Materials Lab
Our lab studies the mechanics of biological materials and how these properties fail in disease. We also try to draw from biomechanics to design new biomimetic materials that capture some of the rich dynamics and active properties of biology.
We collaborate with fantastic people at McGill and beyond, and we are always looking for new great people to work with.
Putting a spin on tough bioinspired glass
Particle Image Velocimetry (PIV) on epithelial tissue following the Epithelial-to-Mesenchymal Transition (EMT) with Cell Monolayer Deformation Microscopy (CMDM)
Cell micromanipulation with HAIRS substrates
Resolving the mechanobiological interplay between androgen receptor signalling, microenvironment mechanics, cell mechanics, and metastatic prostate cancer progression
A new twist to mechanotransduction of shear
Heterogenous distribution of lamin A/C and high deformation in the region of low lamin A/C density
Cytoskeleton mechanics via actin dynamic crosslinking
High throughput Traction Force Microscopy for cancer cell mechanics
Cancer mechanics and elastic gradient substrate
Dynamic YAP localization in contractile 3T3 cells
Mechanics of Disease
How do cell mechanics contribute to pathology?
Soft Condensed Matter Physics
Can we understand biological mechanics using physics?
How do cells sense and respond to force?
Biomimetic Materials Science
Can we recreate the amazing mechanics of biology?
Group research discussion
Our research discussion meeting is held on Tuesdays 9:30 - 11:30 am via Zoom, where every week several members of the lab and occasionally visitors or collaborators may present work.
This meeting is open to members and invited guests. Please email firstname.lastname@example.org to learn more.
The Biological and Biomedical Engineering Research Seminar is on Fridays 1:30 - 2:30 pm, and is typically held in-person in DUFF 507/509 and/or virtually via Zoom. Please check the seminar schedule for the most up-to-date information.